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immortalized human bone marrow msc cell line  (ATCC)
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ATCC immortalized human bone marrow msc cell line
The tests of modified MSCs using CRISPR-Cas9 technology
Immortalized Human Bone Marrow Msc Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bone marrow derived hmsc  (Biowhittaker Inc)
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Biowhittaker Inc bone marrow derived hmsc
The tests of modified MSCs using CRISPR-Cas9 technology
Bone Marrow Derived Hmsc, supplied by Biowhittaker Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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human bone marrow-derived mscs hmsc  (Kurabo industries)
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Kurabo industries human bone marrow-derived mscs hmsc
The tests of modified MSCs using CRISPR-Cas9 technology
Human Bone Marrow Derived Mscs Hmsc, supplied by Kurabo industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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The tests of modified MSCs using CRISPR-Cas9 technology

Journal: Journal of Hematology & Oncology

Article Title: Challenges and advances in clinical applications of mesenchymal stromal cells

doi: 10.1186/s13045-021-01037-x

Figure Lengend Snippet: The tests of modified MSCs using CRISPR-Cas9 technology

Article Snippet: Immortalized human bone marrow MSC cell line (ATCC PCS-500–041) , PUMILIO2 (PUM2) , Depletion of PUM2 blocks MSC adipogenesis and enhances osteogenesis. PUM2 works as a negative regulator on the 3′ UTRs of JAK2 and RUNX2 via direct binding. CRISPR/CAS9-mediated gene silencing of Pum2 inhibited lipid accumulation and excessive bone formation , [ ] .

Techniques: Modification, CRISPR, Functional Assay, Synthesized, In Vitro, Transfection, Expressing, Transplantation Assay, Inhibition, Binding Assay